Chuck Perouhttp://genomics.unc.edu/perou/perou_dw.htmshapeimage_2_link_0
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BROWN LAB PUBLICATIONS


Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D "Repeated observation of breast tumor subtypes in independent gene expression data sets." Proc Natl Acad Sci U S A 2003; 100: 14: 8418-23.

van de Rijn M, Perou CM, Tibshirani R, Haas P, Kallioniemi O, Kononen J, Torhorst J, Sauter G, Zuber M, Köchli OR, Mross F, Dieterich H, Seitz R, Ross D, Botstein D, Brown P "Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome." Am J Pathol 2002; 161: 6: 1991-6.

Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO "Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors." Proc Natl Acad Sci U S A 2002; 99: 20: 12963-8.

Whitfield ML, Sherlock G, Saldanha AJ, Murray JI, Ball CA, Alexander KE, Matese JC, Perou CM, Hurt MM, Brown PO, Botstein D "Identification of genes periodically expressed in the human cell cycle and their expression in tumors." Mol Biol Cell 2002; 13: 6: 1977-2000.

Garber ME, Troyanskaya OG, Schluens K, Petersen S, Thaesler Z, Pacyna-Gengelbach M, van de Rijn M, Rosen GD, Perou CM, Whyte RI, Altman RB, Brown PO, Botstein D, Petersen I "Diversity of gene expression in adenocarcinoma of the lung." Proc Natl Acad Sci U S A 2001; 98: 24: 13784-9.

Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL "Microarrays in primary breast cancer--lessons from chemotherapy studies." Endocr Relat Cancer 2001; 8: 3: 259-63.

Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Eystein Lønning P, Børresen-Dale AL "Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications." Proc Natl Acad Sci U S A 2001; 98: 19: 10869-74.

Finlin BS, Gau CL, Murphy GA, Shao H, Kimel T, Seitz RS, Chiu YF, Botstein D, Brown PO, Der CJ, Tamanoi F, Andres DA, Perou CM "RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer." J Biol Chem 2001; 276: 45: 42259-67.

Liu R, Liu H, Chen X, Kirby M, Brown PO, Zhao K "Regulation of CSF1 promoter by the SWI/SNF-like BAF complex." Cell 2001; 106: 3: 309-18.

Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D "Molecular portraits of human breast tumours." Nature 2000; 406: 6797: 747-52.

Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D, Brown PO "Systematic variation in gene expression patterns in human cancer cell lines." Nat Genet 2000; 24: 3: 227-35.

Scherf, U., Ross, D.T., Waltham, M., Smith, L.H., Lee, J., Kohn, K.W., Reinhold, W.C., Myers, T., Andrews, D.T., Scudiero, D.A., Eisen, M.B., Sausville, E.A., Pommier, Y., Botstein, D., Brown, P.O.  and Weinstein, J.N. 2000. A gene expression database for the molecular pharmacology of cancer. Nature Genetics 24: 236-244.

Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D, Brown PO, Botstein D "Distinctive gene expression patterns in human mammary epithelial cells and breast cancers." Proc Natl Acad Sci U S A 1999; 96: 16: 9212-7.

Pollack JR, Perou CM, Alizadeh AA, Eisen MB, Pergamenschikov A, Williams CF, Jeffrey SS, Botstein D, Brown PO "Genome-wide analysis of DNA copy-number changes using cDNA microarrays." Nat Genet 1999; 23: 1: 41-6.